Clinical Trials - HIV-associated cancers - completed studies

Completed studies in HIV-associated cancers

Our completed HPV-related clinical trials are listed below:

NCT00604175

Protocol number title: Evaluation of Immunogenicity and Safety of a Quadrivalent Human Papillomavirus Vaccine in HIV-1 Infected Females

PI Interventional / Observational Closed/ Ongoing Start/
end date
Network Funders/ sponsors
Dr Firnhaber Interventional Closed 2008/2011 AIDS Clinical Trials Group (ACTG) National Institutes of Health (NIH)

NCT to follow

Protocol number title: Screening for anal dysplasia by using anal cytology and human papillomavirus (HPV) testing in HIV-infected women from Johannesburg, South Africa

PI Interventional / Observational Closed/ Ongoing Start/
end date
Investigator driven trials Funders/ sponsors
Dr Firnhaber/Dr Jong Observational Closed 2012 National Institutes of Health (NIH)

NCT01315353

Protocol number title: HPV Test-and-Treat Study

PI Interventional / Observational Closed/ Ongoing Start/
end date
Network Funders/ sponsors
Dr Firnhaber Interventional Closed 2011/Dec 2016 AIDS Clinical Trials Group (ACTG) National Institutes of Health (NIH)

Completed studies in HIV-associated cancers

NCT01590017

Protocol number title: Cisplatin and Radiation Therapy in Treating Patients With HIV-Associated Locally Advanced Cervical Cancer

PI Interventional / Observational Closed/ Ongoing Start/
end date
Network Funders/ sponsors
Dr Mark H. Einstein Interventional Closed April 2017 AIDS Malignancy Consortium AIDS Malignancy Consortium

Protocol number title: A Randomized, Placebo-Controlled Trial of Pre-Treatment HPV Vaccination on Outcomes to LEEP Treatment of Cervical High Grade Squamous Intraepithelial Lesions in HIV-Infected Women

PI Interventional / Observational Closed/ Ongoing Start/
end date
Investigator driven trials Funders/ sponsors
Dr Firnhaber Observational Ongoing Unspecified MERCK/MSD

Completed studies in Karposi Sarcoma

NCT01435018

Protocol number title: A Randomized Comparison of Three Regimens of Chemotherapy with Compatible Antiretroviral Therapy for Treatment of Advanced AIDS-KS in Resource-Limited Settings (current).

PI Interventional / Observational Closed/ Ongoing Start/
end date
Network Funders/ sponsors
Dr Sanne Interventional Follow-up Jul-05 AIDS Clinical Trials Group (ACTG) National Institutes of Health (NIH)

NCT01352117

Protocol number title: ART Alone or with/Delayed Chemo vs ART w/Immediate Chemo for Limited AIDS-KS

PI Interventional / Observational Closed/ Ongoing Start/
end date
Network Funders/ sponsors
Dr Mwelase Interventional Closed 2011 – 2018 AIDS Clinical Trials Group (ACTG) National Institutes of Health (NIH)

Other completed HIV-associated cancer studies

Protocol number title: Effect of trichomoniasis therapy on genital HIV viral burden amongst African women

PI Interventional / Observational Closed/ Ongoing Start/
end date
Investigator driven trials Funders/ sponsors
Dr Firnhaber Interventional Closed 2007-2008 National Institutes of Health (NIH)

NCT02250716

Protocol number title: Immediate treatment of CIN1 with Cryotherapy versus regular 12-month cytology follow-up in HIV-positive women

PI Interventional / Observational Closed/ Ongoing Start/
end date
Network Funders/ sponsors
Dr Firnhaber/Dr Mayisela Interventional Closed 2012-2016 Investigator driven trials National Institutes of Health (NIH)