Clinical Trials - TB - Upcoming studies

Upcoming TB studies

Upcoming clinical trials in TB that CHRU will be undertaking are listed here:

NCT To be confirmed

Protocol number/ title: Clofazimine in drug-susceptible tuberculosis – Optimizing levonorgestrel emergency contraception with ART & Anti-TB therapy.

PI Interventional / Observational Closed/ Ongoing Start/
end date
Network Funders/ sponsors
To be confirmed To be confirmed Pending To be confirmed AIDS Clinical Trials Group (ACTG) National Institutes of Health (NIH)

NCT To be confirmed

Protocol number/ title: Treatment of multidrug resistant tuberculosis (MDR-TB).

PI Interventional / Observational Closed/ Ongoing Start/
end date
Network Funders/ sponsors
To be confirmed To be confirmed Pending To be confirmed AIDS Clinical Trials Group (ACTG) National Institutes of Health (NIH)

NCT To be confirmed

Protocol number/ title: Cycled ultra-short course preventative INH/RPT in HIV in medium to high TB-endemic areas.

PI Interventional / Observational Closed/ Ongoing Start/
end date
Network Funders/ sponsors
To be confirmed To be confirmed Pending To be confirmed AIDS Clinical Trials Group (ACTG) National Institutes of Health (NIH)

NCT03819114

Protocol number/ title: An Open-Label, Phase II Pharmacokinetic Study to Evaluate Double-Dose Levonorgestrel Emergency Contraception in Combination with Efavirenz-Based Antiretroviral Therapy or Rifampicin-Containing Anti-Tuberculosis Therapy.

PI Interventional / Observational Closed/ Ongoing Start/
end date
Network Funders/ sponsors
To be confirmed To be confirmed Pending To be confirmed AIDS Clinical Trials Group (ACTG) National Institutes of Health (NIH)

NCT To be confirmed

Protocol number/ title: A drug development program to shorten and simplify treatment of drug sensitive tuberculosis.

PI Interventional / Observational Closed/ Ongoing Start/
end date
Network Funders/ sponsors
To be confirmed To be confirmed Pending To be confirmed TB Alliance Michael Hoelscher/
Sequella, Inc./
European and Developing Countries Clinical Trials Partnership (EDCTP) and others