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Ground-breaking science and innovative healthcare

South Africa is at the epicentre of the HIV and tuberculosis (TB) epidemics. The Clinical HIV Research Unit (CHRU) runs clinical trials undertaking clinical research to prevent, treat and manage HIV/AIDS, TB and associated diseases. It is a division of the Wits Health Consortium, a wholly owned company of the Faculty of Health Sciences at the University of Witwatersrand (Wits) located in Johannesburg, South Africa. It is affiliated to the Department of Internal Medicine at Wits. Our mission is to deliver excellence and quality in clinical research.

Latest News

Addressing cervical cancer

Cervical cancer is the fourth most common cancer among women globally and the second most common cancer in South African women…

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Treatment time for drug resistant TB slashed

A new ground breaking program which was established to slash treatment time frames for drug resistant TB…

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SA leading the world’s HIV response

SA is leading the world`s response to the HIV epidemic with major research projects in the prevention, treatment and care of people living…

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Our clinical trials focus on three main areas of intervention

HIV/AIDS, TB and HIV-Associated Cancers


  • Treatment in paediatrics and adults and
  • Drug resistance

Tuberculosis (TB)

  • Drug sensitive TB and
  • Multidrug-resistant TB (MDR-TB) and
  • Extensively Drug Resistant TB (XDR-TB)

HIV-associated cancers

  • Kaposi Sarcoma
  • The Human Papillomavirus Virus (HPV) and
  • Cervical Cancer – Screening and Treatment