About CHRU

About the Clinical HIV Research Unit (CHRU)

Filling samples in the centrifuge in the CHRU laboratory
Study participants enjoy world class healthcare services
About CHRU

CHRU contributes to global infectious diseases research

The Clinical HIV Research Unit (CHRU) is a division of the Wits Health Consortium, a wholly-owned company of the Faculty of Health Sciences at the University of the Witwatersrand (Wits).

CHRU is affiliated to the Wits Faculty of Health Sciences Research Office. 

Our multidisciplinary team collaborates with international networks and sponsors to contribute to global research. CHRU studies have advanced national (South Africa’s National Department of Health) and international (World Health Organisation) treatment guidelines. 

With four clinical research sites across South Africa, all our studies comply with the highest ethical standards and regulations. 

CHRU team

Dynamic team of scientists and professionals

The Clinical HIV Research Unit (CHRU) is home to a dynamic team of professionals who bring over two decades of clinical trial experience to the unit. They include scientists/principal investigators, medical officers, study coordinators, healthcare workers, pharmacists, counsellors and staff experienced in clinical trial operations - data management, quality assurance and regulatory.

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CLINICAL RESEARCH SITE The Isango Lethemba TB Research Unit team
CLINICAL RESEARCH SITE The King DinuZulu Hospital Clinical Research Site team
CLINICAL RESEARCH SITE Sizwe Tropical Diseases Hospital CRS team
CLINICAL RESEARCH SITE Clinical HIV Research Unit Helen Joseph Hospital Clinical Research Site team
Our departments

The CHRU Departments

The Clinical HIV Research Unit (CHRU) is made up of different departments which together contribute to altering the HIV and TB epidemics in South Africa by supporting the outcome of our world class clinical trials.

Principal Investigators and sub-Investigators play a central role in clinical studies

Investigators and sub-investigators 

Principal Investigators (PIs) are responsible for the preparation, conduct and administration of a research grant or sponsored project.

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DEPT CHRU's data department at the Helen Joseph Hospital CRS

Data management

Data integrity is a cornerstone of CHRU’s clinical trials. Attention to detail by our experienced data management team has continually led to outstanding data management reports, with a 99% average data quality rate.

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The aseptic room at CHRU

Governance

Through the Faculty of Health Sciences at the University of Witwatersrand, the Wits Health Consortium (WHC) provides the governance and legal framework for the Clinical HIV Research Unit (CHRU).

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Administration department team

Operations

CHRU operates according to best international practices, using innovative technology across its operations.

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DEPT CHRU's pharmacy team at the Helen Joseph Hospital CRS run a world class pharmacy

Pharmacy

The Research Pharmacy at CHRU is designed according to world-class specifications and run by an experienced team of pharmacists and pharmacist assistants.

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DEPT CHRU's Quality Assurance department ensures compliance with the principles of research as well as sponsor, regulatory and ethical requirements

Quality assurance department

CHRU strives to maintain gold standards of quality to ensure participant safety, data validity and credibility.

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CHRU's Recruitment and Retention department team

Recruitment and retention

Recruitment and retention of clinical trial participants are paramount to the success of clinical trials.

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DEPT The Regulatory Department at CHRU ensures compliance with international and SA regulations

Clinical trial Regulation

Numerous international and South African regulatory authorities and clinical research bodies govern clinical trials and protect the rights and safety of clinical trial participants.

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DEPT CHRU's study coordinators focus on participant care

Study coordinators

Participant care is one of the key roles of our study coordinators who Anticipate their healthcare needs

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Women’s Cancer Prevention Research

Women’s Cancer Prevention Research

The Clinical HIV Research Unit’s Women’s Cancer Prevention Research Department focuses on improving cervical cancer screening

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Cervical cancer examination room at CHRU
Collaboration

Collaborative research contributes to knowledge base

The Clinical HIV Research Unit (CHRU) has a well-established track record of ongoing funding from multiple sources to support its research activities and technical assistance. This enables strong collaborations for clinical trials.

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Community

Communities central to clinical trials

Communities are central to the success of the studies undertaken by the Clinical HIV Research Unit (CHRU).

Most clinical trial participants live close to CHRU’s four clinical research sites.

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Efficient storage at CHRU ensures research excellence and ongoing collaborations

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1. Participate in a study.
2. Support our community outreach.
3. Find out more about our research.

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